Why are some slope & vertical height values negative?

I cannot work out why 1 of my distance annotations has negative values for the slope and vertical height… what am I missing!?

Are the measurements close to north to south? The reading of the line could be reversed.

No, it runs south west to north east but I have tried re drawing the line in the opposite direction, flipping the line, making small adjustments etc… It still remains in the negative value.

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…and it’s not a downslope - negative grade? The profile always runs left to right no matter what direction you draw the line.

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